Modern Genetics (II) Objectives

-Define linked genes.

-Explain crossing over.

-Compare autosomes with sex chromosomes.

-Explain how sex is determined in humans.

-Define sex-linked traits, give an example, explain why men are more often affected.

-Solve sex-linkage problems.

-Define carrier.

-Interpret pedigree charts.

-Define mutations and explain how they are passed to offspring.

-Compare mutations that affect chromosome number (non-disjunction and polyploidy), and structure (additions/deletions).

-Explain mutations that affect genes.

-Define and give examples of mutagens.

-Explain artificial selection including inbreeding and hybridization.

-Explain the role of the environment in gene expression.

-Describe the following techniques:  Screening, amniocentesis, and karyotyping.

-Describe the following genetic disorders:  Phenylketonuria, sickle-cell anemia, and Tay-Sach’s.